Remote C-H bond functionalization of androstane C-ring: C12-amination

Shuji Yamashita, Masafumi Himuro, Yujiro Hayashi, Masahiro Hirama

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


A new functionalization method for the C-ring of the androstane framework has been established. The key feature is a remote C-H amination, which enables the preparation of the C12-amino, oxo, hydoxy, and C11,12-dehydro derivatives of epiandrosterone.

Original languageEnglish
Pages (from-to)1307-1308
Number of pages2
JournalTetrahedron Letters
Issue number10
Publication statusPublished - 2013 Mar 6


  • Amination
  • Androstane
  • C-H bond functionalization
  • Steroid

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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