Remodeling muscle cells by inducing mechanical stimulus

Kazuaki Mori; Masahiro Shimizu; Kota Miyasaka; Toshihiko Ogura; Koh Hosoda

doi:10.1007/978-3-319-22979-9_23

Remodeling muscle cells by inducing mechanical stimulus

Kazuaki Mori, Masahiro Shimizu, Kota Miyasaka, Toshihiko Ogura, Koh Hosoda

Division of Brain Science

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A muscle cell actuator has been attracting a lot of attention since it is a key technology for realizing bio-machine hybrid systems. This study especially intend to deal with micro robot driven by real muscle cell actuators. To fabricate the actuator, we should study how to control cell aggregation for efficient power generation. This paper proposes a method for remodeling muscle cells by exploiting mechanical stimulus so that we can get an appropriate structure of the actuator. The experimental results demonstrate that the three factors, cell density, cell-matrix adhesion, and mechanical stimulation period, largely contribute to the remodeling of the muscle cells.

Original language	English
Title of host publication	Biomimetic and Biohybrid Systems - 4th International Conference, Living Machines 2015, Proceedings
Editors	Paul F.M.J. Verschure, Stuart P. Wilson, Tony J. Prescott, Anna Mura
Publisher	Springer Verlag
Pages	227-230
Number of pages	4
ISBN (Print)	9783319229782
DOIs	https://doi.org/10.1007/978-3-319-22979-9_23
Publication status	Published - 2015
Event	4th International Conference on Biomimetic and Biohybrid Systems, Living Machines 2015 - Barcelona, Spain Duration: 2015 Jul 28 → 2015 Jul 31

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	9222
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Other

Other	4th International Conference on Biomimetic and Biohybrid Systems, Living Machines 2015
Country	Spain
City	Barcelona
Period	15/7/28 → 15/7/31

Keywords

Bio-machine hybrid system
Mechanical stimulus
Muscle cells actuator
Remodeling

ASJC Scopus subject areas

Theoretical Computer Science
Computer Science(all)

Access to Document

10.1007/978-3-319-22979-9_23

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Mori, K., Shimizu, M., Miyasaka, K., Ogura, T., & Hosoda, K. (2015). Remodeling muscle cells by inducing mechanical stimulus. In P. F. M. J. Verschure, S. P. Wilson, T. J. Prescott, & A. Mura (Eds.), Biomimetic and Biohybrid Systems - 4th International Conference, Living Machines 2015, Proceedings (pp. 227-230). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 9222). Springer Verlag. https://doi.org/10.1007/978-3-319-22979-9_23

Remodeling muscle cells by inducing mechanical stimulus. / Mori, Kazuaki; Shimizu, Masahiro; Miyasaka, Kota; Ogura, Toshihiko; Hosoda, Koh.

Biomimetic and Biohybrid Systems - 4th International Conference, Living Machines 2015, Proceedings. ed. / Paul F.M.J. Verschure; Stuart P. Wilson; Tony J. Prescott; Anna Mura. Springer Verlag, 2015. p. 227-230 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 9222).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Mori, K, Shimizu, M, Miyasaka, K, Ogura, T & Hosoda, K 2015, Remodeling muscle cells by inducing mechanical stimulus. in PFMJ Verschure, SP Wilson, TJ Prescott & A Mura (eds), Biomimetic and Biohybrid Systems - 4th International Conference, Living Machines 2015, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 9222, Springer Verlag, pp. 227-230, 4th International Conference on Biomimetic and Biohybrid Systems, Living Machines 2015, Barcelona, Spain, 15/7/28. https://doi.org/10.1007/978-3-319-22979-9_23

Mori K, Shimizu M, Miyasaka K, Ogura T, Hosoda K. Remodeling muscle cells by inducing mechanical stimulus. In Verschure PFMJ, Wilson SP, Prescott TJ, Mura A, editors, Biomimetic and Biohybrid Systems - 4th International Conference, Living Machines 2015, Proceedings. Springer Verlag. 2015. p. 227-230. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). https://doi.org/10.1007/978-3-319-22979-9_23

Mori, Kazuaki ; Shimizu, Masahiro ; Miyasaka, Kota ; Ogura, Toshihiko ; Hosoda, Koh. / Remodeling muscle cells by inducing mechanical stimulus. Biomimetic and Biohybrid Systems - 4th International Conference, Living Machines 2015, Proceedings. editor / Paul F.M.J. Verschure ; Stuart P. Wilson ; Tony J. Prescott ; Anna Mura. Springer Verlag, 2015. pp. 227-230 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

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