Remodeling muscle cells by inducing mechanical stimulus

Kazuaki Mori, Masahiro Shimizu, Kota Miyasaka, Toshihiko Ogura, Koh Hosoda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A muscle cell actuator has been attracting a lot of attention since it is a key technology for realizing bio-machine hybrid systems. This study especially intend to deal with micro robot driven by real muscle cell actuators. To fabricate the actuator, we should study how to control cell aggregation for efficient power generation. This paper proposes a method for remodeling muscle cells by exploiting mechanical stimulus so that we can get an appropriate structure of the actuator. The experimental results demonstrate that the three factors, cell density, cell-matrix adhesion, and mechanical stimulation period, largely contribute to the remodeling of the muscle cells.

Original languageEnglish
Title of host publicationBiomimetic and Biohybrid Systems - 4th International Conference, Living Machines 2015, Proceedings
EditorsPaul F.M.J. Verschure, Stuart P. Wilson, Tony J. Prescott, Anna Mura
PublisherSpringer Verlag
Pages227-230
Number of pages4
ISBN (Print)9783319229782
DOIs
Publication statusPublished - 2015
Event4th International Conference on Biomimetic and Biohybrid Systems, Living Machines 2015 - Barcelona, Spain
Duration: 2015 Jul 282015 Jul 31

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume9222
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other4th International Conference on Biomimetic and Biohybrid Systems, Living Machines 2015
CountrySpain
CityBarcelona
Period15/7/2815/7/31

Keywords

  • Bio-machine hybrid system
  • Mechanical stimulus
  • Muscle cells actuator
  • Remodeling

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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