The enantioselective glyoxylate-ene reaction catalysed by chiral titanium complex derived from partially resolved BINOL is found to exhibit a remarkable level of asymmetric amplification, wherein the optical yield of the product significantly exceeds the enantiomeric purity of the chiral auxiliary employed.
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1990 Dec 1|
ASJC Scopus subject areas
- Molecular Medicine