Relationship between the time, yield, and enantiomeric excess of asymmetric autocatalysis of chiral 2-alkynyl-5-pyrimidyl alkanol with amplification of enantiomeric excess

Itaru Sato, Daisuke Omiya, Hiroyoshi Igarashi, Keiichi Kato, Yoshihiro Ogi, Koichi Tsukiyama, Kenso Soai

Research output: Contribution to journalArticlepeer-review

111 Citations (Scopus)

Abstract

Experimental and kinetic analysis of asymmetric autocatalysis with amplification of ee in the enantioselective addition of diisopropylzinc to 2-alkynylpyrimidine-5-carbaldehyde using chiral 2-alkynyl-5-pyrimidyl alkanol with low ee's are described.

Original languageEnglish
Pages (from-to)975-979
Number of pages5
JournalTetrahedron Asymmetry
Volume14
Issue number8
DOIs
Publication statusPublished - 2003 Apr 18

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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