Relationship between the time, yield, and enantiomeric excess of asymmetric autocatalysis of chiral 2-alkynyl-5-pyrimidyl alkanol with amplification of enantiomeric excess

Itaru Sato; Daisuke Omiya; Hiroyoshi Igarashi; Keiichi Kato; Yoshihiro Ogi; Koichi Tsukiyama; Kenso Soai

doi:10.1016/S0957-4166(03)00164-2

Relationship between the time, yield, and enantiomeric excess of asymmetric autocatalysis of chiral 2-alkynyl-5-pyrimidyl alkanol with amplification of enantiomeric excess

Itaru Sato, Daisuke Omiya, Hiroyoshi Igarashi, Keiichi Kato, Yoshihiro Ogi, Koichi Tsukiyama, Kenso Soai

Research output: Contribution to journal › Article › peer-review

121 Citations (Scopus)

Abstract

Experimental and kinetic analysis of asymmetric autocatalysis with amplification of ee in the enantioselective addition of diisopropylzinc to 2-alkynylpyrimidine-5-carbaldehyde using chiral 2-alkynyl-5-pyrimidyl alkanol with low ee's are described.

Original language	English
Pages (from-to)	975-979
Number of pages	5
Journal	Tetrahedron Asymmetry
Volume	14
Issue number	8
DOIs	https://doi.org/10.1016/S0957-4166(03)00164-2
Publication status	Published - 2003 Apr 18
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1016/S0957-4166(03)00164-2

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title = "Relationship between the time, yield, and enantiomeric excess of asymmetric autocatalysis of chiral 2-alkynyl-5-pyrimidyl alkanol with amplification of enantiomeric excess",

abstract = "Experimental and kinetic analysis of asymmetric autocatalysis with amplification of ee in the enantioselective addition of diisopropylzinc to 2-alkynylpyrimidine-5-carbaldehyde using chiral 2-alkynyl-5-pyrimidyl alkanol with low ee's are described.",

author = "Itaru Sato and Daisuke Omiya and Hiroyoshi Igarashi and Keiichi Kato and Yoshihiro Ogi and Koichi Tsukiyama and Kenso Soai",

note = "Funding Information: This work was supported by a Grant-in-Aid from Ministry of Education, Culture, Sports, Science and Technology, and New Energy and Industrial Technology Development Organization (NEDO).",

year = "2003",

month = apr,

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doi = "10.1016/S0957-4166(03)00164-2",

language = "English",

volume = "14",

pages = "975--979",

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TY - JOUR

T1 - Relationship between the time, yield, and enantiomeric excess of asymmetric autocatalysis of chiral 2-alkynyl-5-pyrimidyl alkanol with amplification of enantiomeric excess

AU - Sato, Itaru

AU - Omiya, Daisuke

AU - Igarashi, Hiroyoshi

AU - Kato, Keiichi

AU - Ogi, Yoshihiro

AU - Tsukiyama, Koichi

AU - Soai, Kenso

N1 - Funding Information: This work was supported by a Grant-in-Aid from Ministry of Education, Culture, Sports, Science and Technology, and New Energy and Industrial Technology Development Organization (NEDO).

PY - 2003/4/18

Y1 - 2003/4/18

N2 - Experimental and kinetic analysis of asymmetric autocatalysis with amplification of ee in the enantioselective addition of diisopropylzinc to 2-alkynylpyrimidine-5-carbaldehyde using chiral 2-alkynyl-5-pyrimidyl alkanol with low ee's are described.

AB - Experimental and kinetic analysis of asymmetric autocatalysis with amplification of ee in the enantioselective addition of diisopropylzinc to 2-alkynylpyrimidine-5-carbaldehyde using chiral 2-alkynyl-5-pyrimidyl alkanol with low ee's are described.

UR - http://www.scopus.com/inward/record.url?scp=0037453377&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037453377&partnerID=8YFLogxK

U2 - 10.1016/S0957-4166(03)00164-2

DO - 10.1016/S0957-4166(03)00164-2

M3 - Article

AN - SCOPUS:0037453377

VL - 14

SP - 975

EP - 979

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

SN - 0957-4166

IS - 8

ER -

Relationship between the time, yield, and enantiomeric excess of asymmetric autocatalysis of chiral 2-alkynyl-5-pyrimidyl alkanol with amplification of enantiomeric excess

Abstract

ASJC Scopus subject areas

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