Relationship between the β3-adrenoceptor gene variant and body fat in Japanese children

Naoyuki Kurokawa, Kunihiko Nakai, Satomi Kameo, Zhong Min Liu, Hiroshi Satoh

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

In this study, we investigated whether the variant of the β3-adrenoceptor gene is associated with accumulation of body fat in Japanese junior high school students. A total of 87 junior high school students, 50 boys and 37 girls, participated in this survey. The β3-adrenoceptor gene variant was detected by polymerase chain reaction-restriction fragment length polymorphism. (PCR-RFLP). Accumulation of body fat was assessed by skinfold thickness at the triceps and subscapular with a skinfold caliper. There was no difference between boys and girls in the frequency of the β3-adrenoceptor gene allele. There were no significant differences in body mass index and percent body fat between the Arg carriers (Trp/Arg or Arg/Arg) and the Arg noncarriers (Trp/Trp) for either sex. The Trp64Arg variant of the β3-adrenoceptor gene does not seem to have a strong effect on the accumulation of body fat in this group of Japanese junior high school students.

Original languageEnglish
Pages (from-to)271-276
Number of pages6
JournalTohoku Journal of Experimental Medicine
Volume201
Issue number4
DOIs
Publication statusPublished - 2003 Dec

Keywords

  • Body fat
  • Children
  • Trp64Arg
  • β-adrenoceptor gene variant

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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