The tensile, plain, and fretting fatigue characteristics of the newly developed beta type titanium alloy, Ti-29Nb-13Ta-4.6Zr (TNTZ) were investigated for biomedical applications. The forged TNTZ aged at 723 K after solution treatment had a relatively excellent balance of tensile strength and elongation. The plain fatigue limit of TNTZ aged at 673 K or 723 K after solution treatment was found to be about 700 MPa. The plain fatigue strength of TNTZ conducted with solution treatment was nearly equal to that in Ringer's solution. The results show that in fretting fatigue in Ringer's solution, the passive film on surface is broken by fretting action in TNTZ, which forms corrosion pits leading to decrease in fretting fatigue strength.