Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80

Atsushi Hozawa, Tomonori Okamura, Izumi Oki, Yoshitaka Murakami, Takashi Kadowaki, Koshi Nakamura, Naomi Miyamatsu, Takehito Hayakawa, Yoshikuni Kita, Yosikazu Nakamura, Yasuyuki Nakamura, Robert D. Abbott, Akira Okayama, Hirotsugu Ueshima, Osamu Iimura, Teruo Omae, Kazuo Ueda, Hiroshi Yanagawa, Hiroshi Horibe, Kazunori KodamaFumiyoshi Kasagi, Shinichi Tanihara, Shigeyuki Saito, Kiyomi Sakata, Fumihiko Kakuno, Toshihiro Takeuchi, Mitsuru Hasebe, Fumitsugu Kusano, Takahisa Kawamoto, Masumi Minowa, Minoru Iida, Tsutomu Hashimoto, Shigemichi Tanaka, Atsushi Terao, Katsuhiko Kawaminami, Koryo Sawai, Shigeo Shibata

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

As body composition in Asian populations is largely different from Western populations, a healthy BMI could also differ between the two populations. Thus, further study is needed to determine whether a healthy BMI in Asians should be lower than Western populations, as recommended by the World Health Organization (WHO). We investigated the relationship between BMI and mortality in a sample of 8,924 Japanese men and women without stroke or heart disease. During 19 years of follow-up, 1,718 deaths were observed. We found a U-shaped relationship between BMI and fatal events. Risk of total mortality was highest in participants with BMI <18.5 kg/m2 and lowest in participants with BMI 23.0-24.9 kg/m2. These findings persisted even after excluding the first 5 years of follow-up with a focus on healthy participants who never smoked, were aged <70 years, and had total cholesterol (TC) levels ≥4.1 mmol/l (N = 3712). For both the full sample and healthy participants, all-cause mortality risk did not differ between BMI ranges 21.0-22.9 and 23.0-24.9 kg/m2. Our findings do not support the recent WHO implications that BMIs <23.0 kg/m2 is healthy for Asians. Therefore, further studies are needed to identify an optimal BMI range for Asia.

Original languageEnglish
Pages (from-to)1714-1717
Number of pages4
JournalObesity
Volume16
Issue number7
DOIs
Publication statusPublished - 2008 Jul 1
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

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    Hozawa, A., Okamura, T., Oki, I., Murakami, Y., Kadowaki, T., Nakamura, K., Miyamatsu, N., Hayakawa, T., Kita, Y., Nakamura, Y., Nakamura, Y., Abbott, R. D., Okayama, A., Ueshima, H., Iimura, O., Omae, T., Ueda, K., Yanagawa, H., Horibe, H., ... Shibata, S. (2008). Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80. Obesity, 16(7), 1714-1717. https://doi.org/10.1038/oby.2008.237