Relation of C-reactive protein and one-year survival after acute myocardial infarction with versus without statin therapy

Kunihiro Kinjo, Hiroshi Sato, Yasuhiko Sakata, Daisaku Nakatani, Hiroya Mizuno, Masahiko Shimizu, Masami Nishino, Hiroshi Ito, Jun Tanouchi, Shinsuke Nanto, Masatsugu Hori

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We evaluated the interaction between inflammation and survival benefit from statin therapy in patients who had acute myocardial infarction. Although 1-year mortality did not differ between patients who used statin therapy and those who did not, among patients who had C-reactive protein (CRP) concentrations in the lower 2 tertiles (<2.9 mg/L), 1-year mortality was higher in patients who used statin therapy than in those who did not within the highest CRP-defined tertile (<2.9 mg/L). Statin therapy significantly decreased the hazard ratio for 1-year mortality in patients who had high CRP levels to approximately the hazard present for patients who had low CRP levels and did not receive statin therapy.

Original languageEnglish
Pages (from-to)617-621
Number of pages5
JournalAmerican Journal of Cardiology
Volume96
Issue number5
DOIs
Publication statusPublished - 2005 Sep 1
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Relation of C-reactive protein and one-year survival after acute myocardial infarction with versus without statin therapy'. Together they form a unique fingerprint.

  • Cite this

    Kinjo, K., Sato, H., Sakata, Y., Nakatani, D., Mizuno, H., Shimizu, M., Nishino, M., Ito, H., Tanouchi, J., Nanto, S., & Hori, M. (2005). Relation of C-reactive protein and one-year survival after acute myocardial infarction with versus without statin therapy. American Journal of Cardiology, 96(5), 617-621. https://doi.org/10.1016/j.amjcard.2005.04.030