Relatedness between the coagulase gene 3′-end region and coagulase serotypes among Staphylococcus aureus strains

Keiji Kanemitsu, Hiroyuki Yamamoto, Hiromu Takemura, Mitsuo Kaku, Jingoro Shimada

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The 3′-end region of the coagulase gene from 22 strains of Staphylococcus aureus including 10 standard serotype strains was sequenced, and five subgroups with 4-8 tandem repeating units were distinguished among the tested strains. Phylogenetic analysis of the 3′-end region of the coagulase gene indicated that strains belonging to the same serotype were clustered in the same branch. A phylogenetic tree of the deduced amino acid sequences revealed that the C-terminal region might not be responsible for the epitope of the coagulase protein.

Original languageEnglish
Pages (from-to)23-27
Number of pages5
JournalMICROBIOLOGY and IMMUNOLOGY
Volume45
Issue number1
DOIs
Publication statusPublished - 2001 Jan

Keywords

  • Coagulase serotype
  • Sequence analysis
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Virology

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