Rehabilitation using repetitive transcranial magnetic stimulation

Naoyuki Takeuchi, Shin Ichi Izum

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Various novel stroke rehabilitative methods have been developed based on findings in basic science and clinical research. Recently, many reports have shown that repetitive transcranial magnetic stimulation (rTMS) improves function in stroke patients by altering the excitability of the human cortex. The interhemispheric competition model proposes that deficits in stroke patients are due to reduced output from the affected hemisphere and excessive interhemispheric inhibition from the unaffected hemisphere to the affected hemisphere. The interhemispheric competition model indicates that improvement in deficits can be achieved either by increasing the excitability of the affected hemisphere using excitatory rTMS or by decreasing the excitability of the unaffected hemisphere using inhibitory rTMS. Recovery after stroke is related to neural plasticity, which involves developing new neural connections, acquiring new functions, and compensating for impairments. Artificially modulating the neural network by rTMS may induce a more suitable environment for use-dependent plasticity and also may interfere with maladaptive neural activation, which weakens function and limits recovery. There is potential, therefore, for rTMS to be used as an adjuvant therapy for developed neurorehabilitation techniques in stroke patients.

Original languageEnglish
Pages (from-to)227-238
Number of pages12
JournalBrain and Nerve
Issue number3
Publication statusPublished - 2017 Mar


  • Aphasia
  • Dysphagia
  • Rehabilitation
  • Repetitive transcranial magnetic stimulation
  • Stroke
  • Unilateral spatial neglect

ASJC Scopus subject areas

  • Clinical Neurology


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