Rehabilitating patients with hepatopulmonary syndrome using living-related orthotopic liver transplant: A case report

Masahiro Kohzuki, Takahumi Abo, Mihoko Watanabe, Yoko Goto, Nobuhiro Ohkohchi, Susumu Satomi, Tokutaro Sato

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The objective of this study was to rehabilitate a patient with hepatopulmonary syndrome (HPS) who underwent living-related orthotopic liver transplantation (LT). HPS is rare; it presents severe complication in patients with liver disease. A 17-year-old woman with HPS developed portal hypertension after undergoing Kasai's surgery for congenital biliary atresia and underwent a living-related orthotopic LT. After LT, her allograft functioned well, but she continued to have hypoxemia and orthodeoxia. She was referred for rehabilitation for disuse atrophy, contracture of hip and shoulder joints, left common peroneal nerve palsy, and rehabilitation for respiratory dysfunction. By day 106 after LT, her orthodeoxia and disuse atrophy had improved because of daily exercise training and active joint range of motion exercises. Patients with HPS have orthodeoxia and poor responsiveness to oxygen therapy, and correction of hypoxemia after LT may be delayed. Therefore, rehabilitation approaches for patients with HPS should be based on the pathophysiology and characteristics of HPS. (C) 2000 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation.

Original languageEnglish
Pages (from-to)1527-1530
Number of pages4
JournalArchives of Physical Medicine and Rehabilitation
Issue number11
Publication statusPublished - 2000


  • Hepatopulmonary syndrome
  • Hypoxemia
  • Liver transplantation
  • Rehabilitation

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


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