Regulation of Necroptosis by Phospholipids and Sphingolipids

Xuewei Zhang, Masaya Matsuda, Nobuo Yaegashi, Takeshi Nabe, Kazuyuki Kitatani

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage kinase domain-like protein. Recent evidence suggests a key role for lipidic molecules in the regulation of necroptosis. The purpose of this mini-review is to outline the regulation of necroptosis by sphingolipids and phospholipids.

Original languageEnglish
JournalCells
Volume9
Issue number3
DOIs
Publication statusPublished - 2020 Mar 5

Keywords

  • ceramide
  • fatty acids
  • lipids
  • mixed lineage kinase-domain like
  • necroptosis
  • phosphatidylinositols

ASJC Scopus subject areas

  • Medicine(all)

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