Abstract
Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage kinase domain-like protein. Recent evidence suggests a key role for lipidic molecules in the regulation of necroptosis. The purpose of this mini-review is to outline the regulation of necroptosis by sphingolipids and phospholipids.
Original language | English |
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Journal | Cells |
Volume | 9 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2020 Mar 5 |
Keywords
- ceramide
- fatty acids
- lipids
- mixed lineage kinase-domain like
- necroptosis
- phosphatidylinositols
ASJC Scopus subject areas
- Medicine(all)