Regulation of catalytic activity of peptide-heme conjugate by conformational change with trifluoroethanol

Seiji Sakamoto, Hidekazu Fukushima, Kazuaki Kudo

Research output: Contribution to journalArticle

Abstract

A peptide-heme conjugate in which two α-helix segments were covalently coupled at the heme propionates was designed, and the relationship between the structure and the peroxidase-like catalytic activity was examined. The activity and coordination state of heme were regulated by the conformational change of peptide induced upon the addition of trifluoroethanol.

Original languageEnglish
Pages (from-to)584-585
Number of pages2
JournalChemistry Letters
Volume35
Issue number6
DOIs
Publication statusPublished - 2006 Jun 5

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'Regulation of catalytic activity of peptide-heme conjugate by conformational change with trifluoroethanol'. Together they form a unique fingerprint.

  • Cite this