Regional kidney function assessment with 123I-hippuran

F. Shishido, Y. Tateno, K. Fukushi, T. Irie, R. Iwata, K. Tamate, K. Suzuki, T. Nakayama, T. Yamasaki, T. Matsumoto, Y. Murakami, H. Ikehira, A. Kurisu

Research output: Contribution to journalArticlepeer-review


Serial renal scintigraphy using I-123-orthoiodohippurate (I-123-hippuran) was performed in cases with suspected abnormal renal function. Iodine-123 of high purity was produced by the cyclotron in our institute, and I-123-hippuran was synthesized by the melting method. Dynamic renal images, subtracted renoparenchymal images, regional renograms, and functional renal images were processed from serial scintigraphic data after intravenous injection of about 2 mCi of I-123-hippuran, and were compared with the time-activity curve constructed for the entire kidney. Serial dynamic renal images with 3 minute intervals indicated the morphological information of shapes and sizes of kidneys. Regional renograms on renal parenchyma and the pelvis were useful to distinguish each function, and renal functional images were also important for assessment of regional function, condensed into one picture. We conclude that these images and time-activity curves processed from dynamic renal scintigrahy with I-123-hippuran provide a useful method to assess renal regional function.

Original languageEnglish
Pages (from-to)1001-1011
Number of pages11
Issue number7
Publication statusPublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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