Amide cuprate reagents attack the less hindered carbon atom of epoxides to give 1,2-amino alcohols in good yields; this procedure is applied to the synthesis of an aziridine alcohol bearing a carborane framework which is a potentially useful 10B carrier for boron neutron capture therapy.
|Number of pages||3|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1993|
ASJC Scopus subject areas
- Molecular Medicine