Refractive-index based tomosynthesis using dark-field imaging optics

N. Sunaguchi, T. Yuasa, S. Ichihara, Q. Huo, M. Sakai, Y. Wu, D. Shimao, M. Ando

Research output: Contribution to journalConference articlepeer-review


Tomosynthesis (TS) is a pseudo-3-dimensional image reconstruction method to recover depth-resolved information using restricted number of projections. In this research, refraction index based TS imaging using dark-field imaging (DFI) optics is proposed and biomedical soft tissues were imaged in low dose exposure. By a single exposure of an object, two projected images are obtained from a Laue-case analyzer of DFI. Calculating the both images refraction component is deduced, while two exposures are needed in DEI (diffraction enhanced imaging). Thus the measurement time and the radiation dose in DFI are half of DEI. In addition, the proposed reconstruction algorithm, derived from the quantitative relationship in measurement process, allows high contrast tomographic imaging in spite of one order smaller number of projections for CT (computed tomography). To demonstrate the proposed imaging protocol efficacy, an ex-vivo excised tissue of human lung were imaged using a system constructed at the vertical wiggler beamline at PF-BL14C at KEK. TS image is successfully delineated high quality soft tissue structures comparable to CT.

Original languageEnglish
Article number192012
JournalJournal of Physics: Conference Series
Issue numberPART 19
Publication statusPublished - 2013
Externally publishedYes
Event11th International Conference on Synchrotron Radiation Instrumentation, SRI 2012 - Lyon, France
Duration: 2012 Jul 92012 Jul 13

ASJC Scopus subject areas

  • Physics and Astronomy(all)


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