TY - JOUR
T1 - Reflection of 18F-FDG accumulation in the evaluation of the extent of periapical or periodontal inflammation
AU - Kito, Shinji
AU - Koga, Hirofumi
AU - Kodama, Masaaki
AU - Yamamoto, Noriaki
AU - Kokuryo, Shinya
AU - Habu, Manabu
AU - Matsuo, Kou
AU - Nishino, Takanobu
AU - Kubota, Kohzoh
AU - Muraoka, Kosuke
AU - Oda, Masafumi
AU - Wakasugi-Sato, Nao
AU - Matsumoto-Takeda, Shinobu
AU - Seta, Yuji
AU - Tanaka, Tatsurou
AU - Miyamoto, Ikuya
AU - Yamashita, Yoshihiro
AU - Kitamura, Chiaki
AU - Nakashima, Keisuke
AU - Takahashi, Tetsu
AU - Tominaga, Kazuhiro
AU - Morimoto, Yasuhiro
PY - 2012/12
Y1 - 2012/12
N2 - Objectives: To elucidate whether fluorine-18-labeled (18F) fluoro-2-deoxy-d-glucose (FDG) accumulation can reflect the extent of periodontal inflammation, periapical inflammation, or dental caries. Study Design: 18F-FDG accumulations on positron emission tomography (PET)-computed tomography (CT) were retrospectively compared with the size of the bone resorption areas caused by periodontal inflammation, periapical inflammation, or dental caries on panoramic radiographs, CT, and magnetic resonance imaging (MRI) in 44 subjects. Results: A significant correlation was found between the size of the bone resorption area caused by periodontal (r = 0.595, P <.01) or periapical (r = 0.560, P <.01) inflammation and the highest standardized uptake value (SUVmax) of 18F-FDG accumulation. A significant correlation was found between the periodontal (r = 0.622, P <.01) or periapical (r = 0.394, P <.01) inflammatory findings on MRI and the SUVmax of 18F-FDG accumulation. The SUVmax of 18F-FDG around most teeth with caries was under 1.5. Conclusions: 18F-FDG accumulation reflects the extent of dental inflammation, not dental caries.
AB - Objectives: To elucidate whether fluorine-18-labeled (18F) fluoro-2-deoxy-d-glucose (FDG) accumulation can reflect the extent of periodontal inflammation, periapical inflammation, or dental caries. Study Design: 18F-FDG accumulations on positron emission tomography (PET)-computed tomography (CT) were retrospectively compared with the size of the bone resorption areas caused by periodontal inflammation, periapical inflammation, or dental caries on panoramic radiographs, CT, and magnetic resonance imaging (MRI) in 44 subjects. Results: A significant correlation was found between the size of the bone resorption area caused by periodontal (r = 0.595, P <.01) or periapical (r = 0.560, P <.01) inflammation and the highest standardized uptake value (SUVmax) of 18F-FDG accumulation. A significant correlation was found between the periodontal (r = 0.622, P <.01) or periapical (r = 0.394, P <.01) inflammatory findings on MRI and the SUVmax of 18F-FDG accumulation. The SUVmax of 18F-FDG around most teeth with caries was under 1.5. Conclusions: 18F-FDG accumulation reflects the extent of dental inflammation, not dental caries.
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U2 - 10.1016/j.oooo.2012.05.027
DO - 10.1016/j.oooo.2012.05.027
M3 - Article
C2 - 23021921
AN - SCOPUS:84869487860
VL - 114
SP - e62-e69
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
SN - 2212-4403
IS - 6
ER -