Reelin, radial fibers and cortical evolution: Insights from comparative analysis of the mammalian and avian telencephalon

Tadashi Nomura, Mitsuharu Hattori, Noriko Osumi

Research output: Contribution to journalReview articlepeer-review

17 Citations (Scopus)

Abstract

The mammalian cerebral cortex has a remarkable laminated structure, which is derived from the pallium, the dorsal part of the embryonic telencephalon. Recent studies indicate that the pallium is developed as a homologous structure in all vertebrate species. However, the cellular and molecular mechanism for making architectural diversity of the pallium is not fully understood. Here we introduce recent progress in comparative analysis of pallial development, and our data on the role of Reelin protein in the developing avian pallium. These experimental approaches to pallial development in non-mammalian species will provide a new insight into evolution of the cerebral cortex.

Original languageEnglish
Pages (from-to)287-297
Number of pages11
JournalDevelopment Growth and Differentiation
Volume51
Issue number3
DOIs
Publication statusPublished - 2009 Apr

Keywords

  • Cerebral cortex
  • Evolution
  • Neuronal specification
  • Radial glia
  • Reelin

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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