Reduction of ethanethiol esters to aldehydes

Hidetoshi Tokuyama, Satoshi Yokoshima, Shao Cheng Lin, Leping Li, Tohru Fukuyama

Research output: Contribution to journalArticlepeer-review

76 Citations (Scopus)

Abstract

Reduction of ethanethiol esters of α-amino acids to α-amino aldehydes by triethylsilane and catalytic palladium-on-carbon is described. α-Amino aldehydes with Boc, Cbz, or Fmoc protection could be obtained without racemization in high yield.

Original languageEnglish
Pages (from-to)1121-1123
Number of pages3
JournalSynthesis
Issue number8
DOIs
Publication statusPublished - 2002
Externally publishedYes

Keywords

  • Aldehydes
  • Amino aldehydes
  • Reductions
  • Thiol esters

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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