Red cell phosphoglucomutase (PGM1) subtypes in Egyptians

Ismail M. Sebetan, Masato Funayama, Kaoru Sagisaka

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The polymorphism of the human red cell phosphoglucomutase1 (PGM1) in samples from Egyptians (n = 134) was investigated using isoelectric focusing in thin-layer polyacrylamide gel. In the studied population samples nine common phenotypes were observed, and the calculated frequencies for the genes PGM11+, PGM11-, PGM12+ and PGM12- were 0.6381, 0.0821, 0.2201 and 0.0597, respectively. The observed and expected phenotypes provide a good fit to Hardy-Weinberg equilibrium. The four alleles system will increase the probability of excluding a man falsely accused of paternity to 30% as compared with 16% if the two alleles system is used.

Original languageEnglish
Pages (from-to)55-59
Number of pages5
JournalForensic Science International
Volume31
Issue number1
DOIs
Publication statusPublished - 1986 May

Keywords

  • Egyptian population
  • Isoelectric focusing
  • PGM polymorphism
  • PGM subtype

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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