Red Blood Cell Aggregation Measurement with 40- MHz Ultrasound Has a Possibility for Noninvasive Evaluation of Blood Glucose Level in Patients with Diabetes

Mototaka Arakawa, Hiroki Sakaki, Kanta Nagasawa, Akiyo Fukase, Shohei Mori, Satoshi Yashiro, Yasushi Ishigaki, Hiroshi Kanai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

To develop methods for noninvasively and quantitatively measuring blood glucose levels (BGL)., the degree of red blood cell (RBC) aggregation at a low shear rate were robustly evaluated by introducing two new parameters determined from changes in the scattering power spectrum of the echoes from the intravascular lumen before and after cessation of blood flow. The clinical significance of these parameters was discussed by comparing them with BGL obtained just before the ultrasonic measurements in one healthy subject. A correlation was found between one of the proposed parameters and BGL. However, the p value was not very high. One of the reasons for the decline of the correlation will be that some factors other than blood glucose also affect RBC aggregation. The proposed method has the potential for clinical application after elucidation of the various factors affecting RBC aggregation.

Original languageEnglish
Title of host publication2018 IEEE International Ultrasonics Symposium, IUS 2018
PublisherIEEE Computer Society
ISBN (Electronic)9781538634257
DOIs
Publication statusPublished - 2018 Dec 17
Event2018 IEEE International Ultrasonics Symposium, IUS 2018 - Kobe, Japan
Duration: 2018 Oct 222018 Oct 25

Publication series

NameIEEE International Ultrasonics Symposium, IUS
Volume2018-October
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Other

Other2018 IEEE International Ultrasonics Symposium, IUS 2018
CountryJapan
CityKobe
Period18/10/2218/10/25

Keywords

  • aggregation
  • blood glucose level
  • red blood cells
  • ultrasound scattering

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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