TY - GEN
T1 - Red Blood Cell Aggregation Measurement with 40- MHz Ultrasound Has a Possibility for Noninvasive Evaluation of Blood Glucose Level in Patients with Diabetes
AU - Arakawa, Mototaka
AU - Sakaki, Hiroki
AU - Nagasawa, Kanta
AU - Fukase, Akiyo
AU - Mori, Shohei
AU - Yashiro, Satoshi
AU - Ishigaki, Yasushi
AU - Kanai, Hiroshi
N1 - Publisher Copyright:
© 2018 IEEE.
PY - 2018/12/17
Y1 - 2018/12/17
N2 - To develop methods for noninvasively and quantitatively measuring blood glucose levels (BGL)., the degree of red blood cell (RBC) aggregation at a low shear rate were robustly evaluated by introducing two new parameters determined from changes in the scattering power spectrum of the echoes from the intravascular lumen before and after cessation of blood flow. The clinical significance of these parameters was discussed by comparing them with BGL obtained just before the ultrasonic measurements in one healthy subject. A correlation was found between one of the proposed parameters and BGL. However, the p value was not very high. One of the reasons for the decline of the correlation will be that some factors other than blood glucose also affect RBC aggregation. The proposed method has the potential for clinical application after elucidation of the various factors affecting RBC aggregation.
AB - To develop methods for noninvasively and quantitatively measuring blood glucose levels (BGL)., the degree of red blood cell (RBC) aggregation at a low shear rate were robustly evaluated by introducing two new parameters determined from changes in the scattering power spectrum of the echoes from the intravascular lumen before and after cessation of blood flow. The clinical significance of these parameters was discussed by comparing them with BGL obtained just before the ultrasonic measurements in one healthy subject. A correlation was found between one of the proposed parameters and BGL. However, the p value was not very high. One of the reasons for the decline of the correlation will be that some factors other than blood glucose also affect RBC aggregation. The proposed method has the potential for clinical application after elucidation of the various factors affecting RBC aggregation.
KW - aggregation
KW - blood glucose level
KW - red blood cells
KW - ultrasound scattering
UR - http://www.scopus.com/inward/record.url?scp=85060649179&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85060649179&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2018.8580086
DO - 10.1109/ULTSYM.2018.8580086
M3 - Conference contribution
AN - SCOPUS:85060649179
T3 - IEEE International Ultrasonics Symposium, IUS
BT - 2018 IEEE International Ultrasonics Symposium, IUS 2018
PB - IEEE Computer Society
T2 - 2018 IEEE International Ultrasonics Symposium, IUS 2018
Y2 - 22 October 2018 through 25 October 2018
ER -
