Recovery of state-specific potential of molecular motor from single-molecule trajectory

Shoichi Toyabe, Hiroshi Ueno, Eiro Muneyuki

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We have developed a novel method to evaluate the potential profile of a molecular motor at each chemical state from only the probe's trajectory and applied it to a rotary molecular motor F 1-ATPase. By using this method, we could also obtain the information regarding the mechanochemical coupling and energetics. We demonstrate that the position-dependent transition of the chemical states is the key feature for the highly efficient free-energy transduction by F 1-ATPase.

Original languageEnglish
Article number40004
JournalEPL
Volume97
Issue number4
DOIs
Publication statusPublished - 2012 Feb 1
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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