Recent progress in electrochemical biosensors for glycoproteins

Uichi Akiba, Jun Ichi Anzai

Research output: Contribution to journalReview articlepeer-review

14 Citations (Scopus)

Abstract

This review provides an overview of recent progress in the development of electrochemical biosensors for glycoproteins. Electrochemical glycoprotein sensors are constructed by combining metal and carbon electrodes with glycoprotein-selective binding elements including antibodies, lectin, phenylboronic acid and molecularly imprinted polymers. A recent trend in the preparation of glycoprotein sensors is the successful use of nanomaterials such as graphene, carbon nanotube, and metal nanoparticles. These nanomaterials are extremely useful for improving the sensitivity of glycoprotein sensors. This review focuses mainly on the protocols for the preparation of glycoprotein sensors and the materials used. Recent improvements in glycoprotein sensors are discussed by grouping the sensors into several categories based on the materials used as recognition elements.

Original languageEnglish
Article number2045
JournalSensors (Switzerland)
Volume16
Issue number12
DOIs
Publication statusPublished - 2016 Dec 1

Keywords

  • Biosensor
  • Electrochemical sensor
  • Glycoprotein
  • Immunosensor
  • Lectin
  • Molecularly imprinted polymers
  • Phenylboronic acid

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Electrical and Electronic Engineering

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