TY - JOUR
T1 - Realistic three-dimensional left ventricular ejection determined from computational fluid dynamics
AU - Taylor, T. W.
AU - Yamaguchi, T.
N1 - Funding Information:
ACKNOWLEDGEMENTS Part of this study was supported by the grant-in-aid for scientific research on priority areas, “Biomechanics of Structure and Function of Living Cells, Tissues, and Organs” (#04237101) and grant #04454537 from the Ministry of Education, Science and Culture of Japan. We also want to thank Dr Hiroyuki Suga, Dr Yoichi Goto, Dr Eats-uya Hata, Dr Toshiyuki Takasago, Dr Akio Saeki and Dr Takehiko Nishioka for their help in making the left ventricular casts at the National Cardiovascular Center Research Institute in Osaka, Japan.
PY - 1995/12
Y1 - 1995/12
N2 - A realistic model of the left ventricle of the human heart was constructed using a cast from a dog heart which was in diastole. A coordinate measuring machine was used to measure and digitize the coordinates of the left ventricle. From the complex measured left ventricle shape values, a three-dimensional finite volume representation was constructed using a simulation package. The left ventricular walls moved towards the centre of the aortic outlet in order to study the effects of time-varying left ventricular ejection. The left ventricular wall motion was assumed to follow the blood flow and the wall grid was reformed 25 times during the calculation. The 25.8 cm3 ventricular volume was reduced by 75% in 0.25 s. Centreline and cross-sectional velocity vectors greatly increased in magnitude at the aortic outlet, and most of the pressure occurred in the top 15% of the heart. The computational method should make it possible to compare simulation results with important measurement techniques such as ultrasound and magnetic resonance imaging, and this should allow a finer detail of flow understanding than is presently available using either a modelling or imaging method alone.
AB - A realistic model of the left ventricle of the human heart was constructed using a cast from a dog heart which was in diastole. A coordinate measuring machine was used to measure and digitize the coordinates of the left ventricle. From the complex measured left ventricle shape values, a three-dimensional finite volume representation was constructed using a simulation package. The left ventricular walls moved towards the centre of the aortic outlet in order to study the effects of time-varying left ventricular ejection. The left ventricular wall motion was assumed to follow the blood flow and the wall grid was reformed 25 times during the calculation. The 25.8 cm3 ventricular volume was reduced by 75% in 0.25 s. Centreline and cross-sectional velocity vectors greatly increased in magnitude at the aortic outlet, and most of the pressure occurred in the top 15% of the heart. The computational method should make it possible to compare simulation results with important measurement techniques such as ultrasound and magnetic resonance imaging, and this should allow a finer detail of flow understanding than is presently available using either a modelling or imaging method alone.
KW - Computational fluid dynamics
KW - boundary fitted coordinate system
KW - cast based modelling
KW - ejection
KW - finite volume method
KW - heart
KW - intracardiac blood flow
KW - left ventricle
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U2 - 10.1016/1350-4533(95)00017-H
DO - 10.1016/1350-4533(95)00017-H
M3 - Article
C2 - 8564155
AN - SCOPUS:0028871279
VL - 17
SP - 602
EP - 608
JO - Medical Engineering and Physics
JF - Medical Engineering and Physics
SN - 1350-4533
IS - 8
ER -