Reactivation of medial temporal lobe and human V5/MT+ during the retrieval of motion information: A PET study

Aya Ueno, Nobuhito Abe, Maki Suzuki, Yayoi Shigemune, Kazumi Hirayama, Etsuro Mori, Manabu Tashiro, Masatoshi Itoh, Toshikatsu Fujii

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Recent neuroimaging evidence suggests that the retrieval of a prior episode reactivates sensory-processing brain regions that were active when the episode was encoded. However, with regard to reactivation of the medial temporal lobe (MTL), the results remain controversial. In the present study, we used positron emission tomography (PET) to identify the brain regions associated with the encoding and retrieval of motion information. Specifically, we assessed whether overlapping activity was found in both the MTL structures and motion-related cortical regions during the encoding and retrieval of motion information attached to meaningless shapes. During the study, subjects were asked to encode moving (rotating to the right or left) and static meaningless shapes. At subsequent testing, subjects were presented with only static shapes, which had been presented with or without motion during encoding, and were engaged in retrieval tasks of shapes and motion. Overlapping activity was found in the right middle temporal gyrus (V5/MT+) and the left MTL (hippocampus) during the encoding and retrieval of shapes with motion compared with those without motion. These results support the view that the retrieval of specific event information is associated with reactivation of both the MTL and the regions involved during the encoding of that information.

Original languageEnglish
Pages (from-to)127-134
Number of pages8
JournalBrain research
Volume1285
DOIs
Publication statusPublished - 2009 Aug 18

Keywords

  • Episodic memory
  • MTL
  • Motion
  • PET
  • Reactivation
  • V5/MT+

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint

Dive into the research topics of 'Reactivation of medial temporal lobe and human V5/MT+ during the retrieval of motion information: A PET study'. Together they form a unique fingerprint.

Cite this