Abstract
The reactions of 2,6-di-tert-butyl-4-methoxyphenyl 2-methoxybenzoate 1a with several organolithium and -magnesium reagents are found to give the methoxy-substitution products 2 and/or the conjugate addition products to the benzoate ring (3 and 4), preferring the latter products at the expense of the former with the increase of the electron-donating ability of the carbanion species. A SET mechanism is proposed for the conjugate addition.
| Original language | English |
|---|---|
| Pages (from-to) | 4821-4824 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 36 |
| Issue number | 27 |
| Publication status | Published - 1995 Jan 1 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry