Abstract
The reactions of 2,6-di-tert-butyl-4-methoxyphenyl 2-methoxybenzoate 1a with several organolithium and -magnesium reagents are found to give the methoxy-substitution products 2 and/or the conjugate addition products to the benzoate ring (3 and 4), preferring the latter products at the expense of the former with the increase of the electron-donating ability of the carbanion species. A SET mechanism is proposed for the conjugate addition.
Original language | English |
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Pages (from-to) | 4821-4824 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 36 |
Issue number | 27 |
Publication status | Published - 1995 Jan 1 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry