Rapid improvement of osseous sarcoidosis after the treatment of pulmonary aspergillosis by itraconazole

K. Murakami, Tsutomu Tamada, K. Abe, M. Nara, S. Hisata, Y. Mitsuishi, S. Muramatsu, K. Gomi, M. Ebina, T. Nukiwa

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Osseous sarcoidosis is relatively uncommon, and treatment with corticosteroids is not always effective. Moreover, patients with an advanced stage of pulmonary sarcoidosis are sometimes infected with aspergillus in the cavities of the pulmonary lesions, and long-term use of corticosteroids should be prohibited to prevent the development of fatal invasive pulmonary aspergillosis. Here, we described a unique case of osseous sarcoidosis with pulmonary aspergillosis, showing a rapid improvement of the osseous symptoms just after the administration of the antifungal agent, itraconazole. Itraconazole is likely to become a candidate among new therapeutic agents for osseous sarcoidosis.

Original languageEnglish
Pages (from-to)75-78
Number of pages4
JournalSarcoidosis Vasculitis and Diffuse Lung Diseases
Volume28
Issue number1
Publication statusPublished - 2011

Keywords

  • Aspergillosis
  • Bone sarcoidosis
  • Corticosteroids
  • Itraconazole

ASJC Scopus subject areas

  • Internal Medicine
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

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