Randomized controlled trial of a water-soluble formulation of lutein in humans

Junya Kobayashi, Etsuko Tominaga, Makoto Ozeki, Tsutomu Okubo, Kiyotaka Nakagawa, Teruo Miyazawa

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Lutein is poorly absorbed owing to their high hydrophobicity and crystallinity. This double-blind crossover trial involved eight healthy males who were administrated capsules containing either a lutein water-soluble formulation or a lutein oil suspension for 8 days. In the formulation group, plasma and erythrocytes lutein concentrations and baseline-corrected AUC were two-fold higher than those in the oil suspension group.

Original languageEnglish
Pages (from-to)2372-2374
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Issue number12
Publication statusPublished - 2019


  • Bioavailability
  • Formulation
  • Lutein

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry


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