Radiofrequency ablation of the liver: Determination of ablative margin at MR imaging with impaired clearance of ferucarbotran - Feasibility study

Kensaku Mori, Kuniaki Fukuda, Hitoshi Asaoka, Takuya Ueda, Akira Kunimatsu, Yoshikazu Okamoto, Katsuhiro Nasu, Kiyoshi Fukunaga, Yukio Morishita, Manabu Minami

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)

Abstract

Institutional review board approval and informed consent were obtained. The feasibility of magnetic resonance (MR) imaging with impaired clearance of ferucarbotran to visualize ablated liver parenchyma surrounding a tumor (ablative margin [AM]) was evaluated after radiofrequency (RF) ablation of the liver. Twenty-one patients with hepatocellular carcinomas underwent RF ablation 2-7 hours after ferucarbotran-enhanced MR imaging. On unenhanced T2*-weighted images acquired after 3-5 days, AMs appeared as hypointense rims. The AM status was related to incidence of residual or recurrent tumors. This technique is feasible for visualization of AM and prediction of residual or recurrent tumors after RF ablation of the liver.

Original languageEnglish
Pages (from-to)557-565
Number of pages9
JournalRadiology
Volume251
Issue number2
DOIs
Publication statusPublished - 2009 May 1
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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