Quantitative digital detection of magnetic beads using pseudo-spin-valve rings for multiplexed bioassays

J. Llandro, T. J. Hayward, D. Morecroft, J. A.C. Bland, F. J. Castaño, I. A. Colin, C. A. Ross

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)

Abstract

We present a magnetic multiplexed assay technology which encodes the identities of target biomolecules according to the moment of magnetic beads to which they are attached. An active digital technique based on a microfabricated magnetoresistive ring-shaped sensor is demonstrated, which can distinguish the magnetic moments of micron-sized superparamagnetic beads. We propose that this development is key to combining nonvolatile magnetic labeling with biochemical libraries for high-throughput bioassays and rapid multiplexed detection.

Original languageEnglish
Article number203904
JournalApplied Physics Letters
Volume91
Issue number20
DOIs
Publication statusPublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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