@article{a28be53d9d6a4b188fb0d6aaff6fffa1,
title = "Quantitative digital detection of magnetic beads using pseudo-spin-valve rings for multiplexed bioassays",
abstract = "We present a magnetic multiplexed assay technology which encodes the identities of target biomolecules according to the moment of magnetic beads to which they are attached. An active digital technique based on a microfabricated magnetoresistive ring-shaped sensor is demonstrated, which can distinguish the magnetic moments of micron-sized superparamagnetic beads. We propose that this development is key to combining nonvolatile magnetic labeling with biochemical libraries for high-throughput bioassays and rapid multiplexed detection.",
author = "J. Llandro and Hayward, {T. J.} and D. Morecroft and Bland, {J. A.C.} and Casta{\~n}o, {F. J.} and Colin, {I. A.} and Ross, {C. A.}",
note = "Funding Information: The authors would like to thank R.B. Balsod and S. Sigurdsson of the Cavendish Laboratory Workshops for design and construction of the sample holder used to perform the measurements, and Professor H. I. Smith (MIT) for use of nanofabrication facilities by which the ring sensors were manufactured. Financial support for the research is gratefully acknowledged from the EPSRC under the Basic Technology Research Programme “4G Project” (J.L., T.J.H, and J.A.C.B.), the Singapore-MIT Alliance (F.J.C., I.A.C., and C.A.R.), and a Marie Curie Fellowship (D.M.).",
year = "2007",
doi = "10.1063/1.2813622",
language = "English",
volume = "91",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics Publising LLC",
number = "20",
}