TY - JOUR
T1 - Quantitative chemocatalytic production of lactic acid from glucose under anaerobic conditions at room temperature
AU - Li, Luyang
AU - Shen, Feng
AU - Smith, Richard L.
AU - Qi, Xinhua
N1 - Funding Information:
This work was supported by the NSFC (no. 21577073), the Natural Science Foundation of Tianjin (no. 16JCZDJC33700) and the Elite Youth program of Chinese Academy of Agricultural Sciences (to Dr Xinhua Qi).
PY - 2017
Y1 - 2017
N2 - Chemical conversion of glucose into lactic acid in water requires harsh reaction conditions to obtain relatively low product yields. Herein, a simple, but highly efficient chemocatalytic process is reported for the production of lactic acid from glucose in the presence of Ba(OH)2 under a nitrogen atmosphere at 1 bar total pressure, where glucose was selectively converted to lactic acid with a yield of 95.4% at room temperature in 48 h. The process was applied to cellobiose, fructose, dihydroxyacetone, glyceraldehyde, pyruvaldehyde and cellulose hydrolysate, among which pyruvaldehyde afforded ca. 100% lactic acid yield. Product distribution changed towards glyceric acid, glycolic acid, formic acid, malonic acid and CO2, by variation of the O2 partial pressure, which promotes the oxidation of glyceraldehyde and 1,3-dihydroxyacetone intermediates. The process developed has significant advantages over previous methods in aspects of efficiency, conditions, reactor materials and productivity.
AB - Chemical conversion of glucose into lactic acid in water requires harsh reaction conditions to obtain relatively low product yields. Herein, a simple, but highly efficient chemocatalytic process is reported for the production of lactic acid from glucose in the presence of Ba(OH)2 under a nitrogen atmosphere at 1 bar total pressure, where glucose was selectively converted to lactic acid with a yield of 95.4% at room temperature in 48 h. The process was applied to cellobiose, fructose, dihydroxyacetone, glyceraldehyde, pyruvaldehyde and cellulose hydrolysate, among which pyruvaldehyde afforded ca. 100% lactic acid yield. Product distribution changed towards glyceric acid, glycolic acid, formic acid, malonic acid and CO2, by variation of the O2 partial pressure, which promotes the oxidation of glyceraldehyde and 1,3-dihydroxyacetone intermediates. The process developed has significant advantages over previous methods in aspects of efficiency, conditions, reactor materials and productivity.
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U2 - 10.1039/c6gc02443b
DO - 10.1039/c6gc02443b
M3 - Article
AN - SCOPUS:85009806863
VL - 19
SP - 76
EP - 81
JO - Green Chemistry
JF - Green Chemistry
SN - 1463-9262
IS - 1
ER -