TY - JOUR
T1 - Quantitative assessment of myocardial enhancement with iodinated contrast medium in patients with ischemic heart disease by using ultrafast X-ray computed tomography
AU - Naito, Hiroaki
AU - Saito, Haruo
AU - Takamiya, Makoto
AU - Hamada, Seiki
AU - Yamada, Naoaki
AU - Imakita, Satoshi
AU - Ohta, Mitsushige
AU - Kimura, Kohji
AU - Tamura, Shinichi
PY - 1992/6
Y1 - 1992/6
N2 - BACKGROUND AND RATIONALE The authors report the quantitation of myocardial enhancement using iodinated contrast medium in patients with ischemic heart disease. Twenty-eight patients with chronic ischemic heart disease and 11 controls were examined by ultrafast computed tomography (CT) using 100-msecond scans. METHODS The authors analyzed M/L (ratio of post-contrast incremental increases in the left ventricular myocardial and luminal CT number) in early and late phases after contrast injection. RESULTS In controls, mean values of early and late M/L were 30% and 51%, respectively. In infarcted or severly ischemic segments, early M/Ls (19%, 16%) were significantly small (P < .001), whereas late M/Ls (90%, 63%) were higher (P < .001, .01) than controls. Segments with infarction or severe ischemia were differentiated from mild or nonsignificant ischemia by using this parameter (sensitivity, 99%; specificity, 88%).
AB - BACKGROUND AND RATIONALE The authors report the quantitation of myocardial enhancement using iodinated contrast medium in patients with ischemic heart disease. Twenty-eight patients with chronic ischemic heart disease and 11 controls were examined by ultrafast computed tomography (CT) using 100-msecond scans. METHODS The authors analyzed M/L (ratio of post-contrast incremental increases in the left ventricular myocardial and luminal CT number) in early and late phases after contrast injection. RESULTS In controls, mean values of early and late M/L were 30% and 51%, respectively. In infarcted or severly ischemic segments, early M/Ls (19%, 16%) were significantly small (P < .001), whereas late M/Ls (90%, 63%) were higher (P < .001, .01) than controls. Segments with infarction or severe ischemia were differentiated from mild or nonsignificant ischemia by using this parameter (sensitivity, 99%; specificity, 88%).
KW - Iodinated contrast medium
KW - Ischemic heart disease
KW - Myocardial infarction
KW - Myocardial ischemia
KW - Ultrafast computed tomography
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U2 - 10.1097/00004424-199206000-00007
DO - 10.1097/00004424-199206000-00007
M3 - Article
C2 - 1607259
AN - SCOPUS:0026638401
VL - 27
SP - 436
EP - 442
JO - Investigative Radiology
JF - Investigative Radiology
SN - 0020-9996
IS - 6
ER -