Quantitative analysis of microstructural components of human cerebral arteries

K. Moritake, H. Handa, A. Okumura, S. Nagasawa, Y. Naruo, K. Hayashi, M. Sato, F. Hazama

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Microstructural components were analyzed quantitatively by means of a microphotometric technique applied to three kinds of major cerebral arteries and two kinds of extracranial arteries of comparable size obtained from human autopsy subjects. No statistically significant difference was found in the fractions of three structural components, elastin (F(e)), collagen (F(c)), and smooth muscle (F(m)) in the total of fractions of these three components and in the ratio of collagen to elastin content (F(C)/F(e)) either between cerebral arteries or between extracranial arteries. The F(e)-values were significantly less in cerebral arteries than in extracranial arteries. The F(c)/F(e) ratios in cerebral arteries were about triple those in extracranial arteries. Although there was no statistically significant difference in the F(e)- and F(m)-values between two age groups, under 49 and over 50 years old, the F(c)-value and the F(c)/F(e) ratio were higher in the older age group. This change of microstructural composition with age was more prominent in cerebral arteries than in extracranial arteries.

Original languageEnglish
Pages (from-to)67-82
Number of pages16
JournalUnknown Journal
Volume3
Issue number1
DOIs
Publication statusPublished - 1981 Jan 1

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Quantitative analysis of microstructural components of human cerebral arteries'. Together they form a unique fingerprint.

Cite this