Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization

H. Yamamoto; K. Nose; N. Itoh; H. Okamoto

doi:10.1007/BF01953722

Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization

H. Yamamoto, K. Nose, N. Itoh, H. Okamoto

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The content of proinsulin mRNA sequences was measured in a cultured cell line established from a transplantable hamster islet cell tumor, by hybridization with proinsulin cDNA. The cells cultured in vitro were found to contain a significant amount of proinsulin mRNA sequences, compared with non-insulin-producing hamster tissues, and seem to be a useful system for the study of insulin gene expression.

Original language	English
Pages (from-to)	187-188
Number of pages	2
Journal	Experientia
Volume	36
Issue number	2
DOIs	https://doi.org/10.1007/BF01953722
Publication status	Published - 1980 Feb
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1007/BF01953722

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title = "Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization",

abstract = "The content of proinsulin mRNA sequences was measured in a cultured cell line established from a transplantable hamster islet cell tumor, by hybridization with proinsulin cDNA. The cells cultured in vitro were found to contain a significant amount of proinsulin mRNA sequences, compared with non-insulin-producing hamster tissues, and seem to be a useful system for the study of insulin gene expression.",

author = "H. Yamamoto and K. Nose and N. Itoh and H. Okamoto",

year = "1980",

month = feb,

doi = "10.1007/BF01953722",

language = "English",

volume = "36",

pages = "187--188",

journal = "Experientia",

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T1 - Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization

AU - Yamamoto, H.

AU - Nose, K.

AU - Itoh, N.

AU - Okamoto, H.

PY - 1980/2

Y1 - 1980/2

N2 - The content of proinsulin mRNA sequences was measured in a cultured cell line established from a transplantable hamster islet cell tumor, by hybridization with proinsulin cDNA. The cells cultured in vitro were found to contain a significant amount of proinsulin mRNA sequences, compared with non-insulin-producing hamster tissues, and seem to be a useful system for the study of insulin gene expression.

AB - The content of proinsulin mRNA sequences was measured in a cultured cell line established from a transplantable hamster islet cell tumor, by hybridization with proinsulin cDNA. The cells cultured in vitro were found to contain a significant amount of proinsulin mRNA sequences, compared with non-insulin-producing hamster tissues, and seem to be a useful system for the study of insulin gene expression.

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DO - 10.1007/BF01953722

M3 - Article

C2 - 6245908

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SN - 1420-682X

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ER -

Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization

Abstract

ASJC Scopus subject areas

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