Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization

H. Yamamoto, K. Nose, N. Itoh, H. Okamoto

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The content of proinsulin mRNA sequences was measured in a cultured cell line established from a transplantable hamster islet cell tumor, by hybridization with proinsulin cDNA. The cells cultured in vitro were found to contain a significant amount of proinsulin mRNA sequences, compared with non-insulin-producing hamster tissues, and seem to be a useful system for the study of insulin gene expression.

Original languageEnglish
Pages (from-to)187-188
Number of pages2
JournalExperientia
Volume36
Issue number2
DOIs
Publication statusPublished - 1980 Feb
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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