Quality of life and functional status of terminally ill head and neck cancer patients: A nation-wide, prospective observational study at tertiary cancer centers in Japan

Takeshi Shinozaki, Mitsuru Ebihara, Satoru Iwase, Takuhiro Yamaguchi, Hitoshi Hirakawa, Wataru Shimbashi, Tomoyuki Kamijo, Makito Okamoto, Takeshi Beppu, Junichiro Ohori, Kazuto Matsuura, Motoyuki Suzuki, Hiroshi Nishino, Yuichiro Sato, Hiroto Ishiki

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Background: Little is known about quality of life and functional status of patients with terminally ill head and neck cancers. Methods: We conducted a multicenter, prospective, observational study to examine quality of life and functional status in terminally ill head and neck cancer patients. Results: Of the 100 patients meeting inclusion criteria, 72 were observed until death. There was no significant difference in the quality of life score between baseline and Week 3. Forty patients (54.9%) could speak and 22 patients (30.5%) could have oral intake upon study entry. Fifty-three patients (74.6%) received enteral nutrition. Twenty-six patients (36.6%) required dressing changes for fungating tumors. The route of nutritional intake (nasogastric tube vs. percutaneous gastric tube) might be predictive for the duration of hospital stay (64 vs. 21 days, P = 0.0372). Conclusion: There was no significant relationship between quality of life and functional status seen in this study. Feeding tube type could have the most impact on quality of life.

Original languageEnglish
Pages (from-to)47-53
Number of pages7
JournalJapanese journal of clinical oncology
Volume47
Issue number1
DOIs
Publication statusPublished - 2017

Keywords

  • Functional status
  • Head and neck cancer
  • Nutrition
  • Prospective observation
  • Terminally ill

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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