Pyoderma gangrenosum (PG) is a rare extracolonic complication of inflammatory bowel disease (IBD), and is known as a complication difficult to manage. Here are three patients with such a complication. Case 1. - A 55- year-old man with ulcerative colitis underwent restorative proctocolectomy. PG on bilateral legs improved postoperatively. Case 2. - A 40- year-old woman with severe ulcerative colitis manifested parastomal ulceration after total proctocolectomy and continent ileostomy. Initial treatment with local stoma care failed to improve the ulceration. The ulceration resolved quickly by systemic medication of prednisolone. Case 3. - A 52-year-old woman with Crohn's disease had PG on the lower limbs. The lesions improved by topical application of corticosteroids. Three patients with PG were treated successfully with surgical, medical or topical treatment.
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