Purification of eicosapentaenoic acid from fish oil with supercritical CO2

Jun Chen, Suzuki Hiromasa, Tadafumi Adschiri, Arai Kunio

Research output: Contribution to journalArticle

Abstract

Concentrating eicosapentaenoic acid (EPA) from fish oil with supercritical CO2 has been carried out using a laboratory rectification column of 9.7mm internal diameter and 1.1m effective height. To improve the supercritical fluid-liquid contact, a scourer rotor was used in the extraction cell, and the column was packed with Dixon ring. Also, to level up the separation ability, the extraction pressure was step-by-step programmed, and the column temperature gradient from bottom to top was kept at 35 to 80°C. Under such conditions, the maximum concentration of EPA was 90%, although plenty of components 20:4 was contained in the experimental feedstock. The work presented shows the possibility of purification of EPA from fish oil with supercritical CO2.

Original languageEnglish
Pages (from-to)757-761
Number of pages5
JournalHuagong Xuebao/Journal of Chemical Industry and Engineering (China)
Volume46
Issue number6
Publication statusPublished - 1995 Dec 1
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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