Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report

Hiromichi Katayama, Hiroshi Aoki, Katsuyuki Taguchi, Yuu Sakurada, Tomonori Sato, Masahiro Takahashi, Rie Shibuya, Hiroshi Naganuma, Shigeto Ishidoya

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report a histologically pure stage 1 seminoma with an elevated human chorionic gonadotropin (hCG). A 38 year-old man was referred for the evaluation of the left testicular swelling. He showed an elevated serum hCG level of 25,265 mIU/ml with normal a fetoprotein and lactate dehydrogenase. Imaging showed heterogeneous tumor without any metastatic lesions. We conducted 4 courses of chemotherapy before detecting hCG nadir. The final pathological report showed pure seminoma with syncytiotrophoblastic cells but no choriocarcinoma components. The patient remains disease free until present time. The case raised several questions regarding diagnosis and treatment strategy for bulky testicular seminoma.

Original languageEnglish
Pages (from-to)48-50
Number of pages3
JournalUrology Case Reports
Volume9
DOIs
Publication statusPublished - 2016 Nov 1
Externally publishedYes

Keywords

  • Seminoma
  • Syncytiotrophoblastic cells
  • hCG

ASJC Scopus subject areas

  • Urology

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