Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report

Hiromichi Katayama; Hiroshi Aoki; Katsuyuki Taguchi; Yuu Sakurada; Tomonori Sato; Masahiro Takahashi; Rie Shibuya; Hiroshi Naganuma; Shigeto Ishidoya

doi:10.1016/j.eucr.2016.08.012

Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report

Hiromichi Katayama, Hiroshi Aoki, Katsuyuki Taguchi, Yuu Sakurada, Tomonori Sato, Masahiro Takahashi, Rie Shibuya, Hiroshi Naganuma, Shigeto Ishidoya

Research output: Contribution to journal › Article

1 Citation (Scopus)

Abstract

We report a histologically pure stage 1 seminoma with an elevated human chorionic gonadotropin (hCG). A 38 year-old man was referred for the evaluation of the left testicular swelling. He showed an elevated serum hCG level of 25,265 mIU/ml with normal a fetoprotein and lactate dehydrogenase. Imaging showed heterogeneous tumor without any metastatic lesions. We conducted 4 courses of chemotherapy before detecting hCG nadir. The final pathological report showed pure seminoma with syncytiotrophoblastic cells but no choriocarcinoma components. The patient remains disease free until present time. The case raised several questions regarding diagnosis and treatment strategy for bulky testicular seminoma.

Original language	English
Pages (from-to)	48-50
Number of pages	3
Journal	Urology Case Reports
Volume	9
DOIs	https://doi.org/10.1016/j.eucr.2016.08.012
Publication status	Published - 2016 Nov 1
Externally published	Yes

Keywords

Seminoma
Syncytiotrophoblastic cells
hCG

ASJC Scopus subject areas

Urology

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title = "Pure Stage I Seminoma with an Elevated hCG of 25,265 mIU/ml: A Case Report",

abstract = "We report a histologically pure stage 1 seminoma with an elevated human chorionic gonadotropin (hCG). A 38 year-old man was referred for the evaluation of the left testicular swelling. He showed an elevated serum hCG level of 25,265 mIU/ml with normal a fetoprotein and lactate dehydrogenase. Imaging showed heterogeneous tumor without any metastatic lesions. We conducted 4 courses of chemotherapy before detecting hCG nadir. The final pathological report showed pure seminoma with syncytiotrophoblastic cells but no choriocarcinoma components. The patient remains disease free until present time. The case raised several questions regarding diagnosis and treatment strategy for bulky testicular seminoma.",

keywords = "Seminoma, Syncytiotrophoblastic cells, hCG",

author = "Hiromichi Katayama and Hiroshi Aoki and Katsuyuki Taguchi and Yuu Sakurada and Tomonori Sato and Masahiro Takahashi and Rie Shibuya and Hiroshi Naganuma and Shigeto Ishidoya",

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doi = "10.1016/j.eucr.2016.08.012",

language = "English",

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T2 - A Case Report

AU - Katayama, Hiromichi

AU - Aoki, Hiroshi

AU - Taguchi, Katsuyuki

AU - Sakurada, Yuu

AU - Sato, Tomonori

AU - Takahashi, Masahiro

AU - Shibuya, Rie

AU - Naganuma, Hiroshi

AU - Ishidoya, Shigeto

PY - 2016/11/1

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