Pulse wave propagation in large blood vessels based on fluid-solid interactions methods

Tomohiro Fukui, Kim H. Parker, Takami Yamaguchi

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)


Pulse Wave Velocity (PWV) is recognized by clinicians as an index of mechanical properties of human blood vessels. This concept is based on the Moens- Korteweg equation, which describes the PWV in ideal elastic tubes. However, measured PWV of real human blood vessels cannot be always interpreted by the Moens-Korteweg equation because this formula is not precisely applicable to living blood vessels. It is important to understand the wave propagation in blood vessels for a more reliable diagnosis of vascular disease. In this study, we modeled uniform arteries in a threedimensional coupled fluid-solid interaction computational scheme, and analyzed the pulse wave propagation. A commercial code (Radioss, Altair Engineering) was used to solve the fluid-solid interactions. We compared the regional PWV values obtained from various computational models with those from the Moens-Korteweg equation, and discuss the accuracy of our computation. The PWV values from the thick-walled artery model are lower than those from the Moens-Korteweg equation. Nevertheless, the differences are less than 7% up to 12 m/s of the PWV, indicating these computational methods for the PWV analysis are accurate enough to evaluate its value quantitatively.

Original languageEnglish
Title of host publicationSingle and Two-Phase Flows on Chemical and Biomedical Engineering
PublisherBentham Science Publishers Ltd.
Number of pages12
ISBN (Print)9781608053476
Publication statusPublished - 2012


  • Arbitrary lagrangian eulerian
  • Arterial wall stiffness
  • Blood flow
  • Fluid-solid interactions
  • Large blood vessels
  • Moens-korteweg equation
  • PWV
  • Pulse wave propagation
  • Sound speed
  • Wave reflection

ASJC Scopus subject areas

  • Engineering(all)


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