Pulmonary arterial impedance analysis by the use of the oscillated assist flow

Tomoyuki Yambe, Kazuhiko Shizuka, Kenji Izutsu, Taro Sonobe, Shigeru Naganuma, Shin Ichi Kobayashi, Shunsuke Nanka, Hiroyuki Hashimoto, Makoto Yoshizawa, Kou Ichi Tabayashi, Hiroshi Takeda, Shin Ichi Nitta

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Pulmonary arterial impedance is an important and interesting characteristic that can be used to evaluate the physiological properties of the pulmonary vessel. However, power spectrum analysis of the pulmonary artery pressure and flow pattern have suggested that peak power in the relatively high frequency range (>10 Hz) is significantly low; thus, we cannot analyze the vessel properties in the high frequency range. In this study, we used the newly developed vibrating flow pump (VFP), which can generate oscillated blood flow with a relatively high frequency (1050 Hz) for right heart bypass, to evaluate the pulmonary arterial impedance pattern in the high frequency range. Acute animal experiments of the right heart bypass from the right atrium to the pulmonary artery using 6 healthy adult goats were performed. The flow pattern and pressure of the pulmonary artery, electrocardiograms (ECGs), and arterial and right atrial pressures were continuously monitored during the experiments. Spectral analysis of the hemodynamic parameters using the fast Fourier transform (FFT) method was performed to evaluate the spectral properties. The coherence function, transfer function, and phase patterns were calculated to analyze the impedance pattern in the relatively high frequency area. Previously, various investigators had tried to analyze the impedance patterns of the pulmonary artery; however, they could not analyze the impedance patterns over 10 Hz because the spectral patterns of the pulmonary flow do not have high power at high frequencies. These physiological analyses may be useful in designing the optimal pulmonary circulation.

Original languageEnglish
Pages (from-to)751-754
Number of pages4
JournalArtificial Organs
Volume21
Issue number7
DOIs
Publication statusPublished - 1997 Jan 1

Keywords

  • Input impedance
  • Oscillated flow
  • Pulmonary arterial impedance
  • Right heart assist
  • Vibrating flow pump

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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  • Cite this

    Yambe, T., Shizuka, K., Izutsu, K., Sonobe, T., Naganuma, S., Kobayashi, S. I., Nanka, S., Hashimoto, H., Yoshizawa, M., Tabayashi, K. I., Takeda, H., & Nitta, S. I. (1997). Pulmonary arterial impedance analysis by the use of the oscillated assist flow. Artificial Organs, 21(7), 751-754. https://doi.org/10.1111/j.1525-1594.1997.tb03735.x