Pt-Pd nanoalloy for the unprecedented activation of carbon-fluorine bond at low temperature

Raghu Nath Dhital, Keigo Nomura, Yoshinori Sato, Setsiri Haesuwannakij, Masahiro Ehara, Hidehiro Sakurai

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Carbon-fluorine bonds are considered the most inert organic functionality and their selective transformation under mild conditions remains challenging. Herein, we report a highly active Pt-Pd nanoalloy as a robust catalyst for the transformation of C-F bonds into C-H bonds at low temperature, a reaction that has hitherto often required harsh conditions. The alloying of Pt with Pd is crucial to promote the overall C-F bond. DFT calculations elucidated that the key step is the selective oxidative addition of the O-H bond of 2-propanol to a Pd center prior to C-F bond activation at a Pt site, which crucially reduces the activation energy of the C-F bond cleavage. Therefore, both Pt and Pd work independently but synergistically to promote the overall reaction.

Original languageEnglish
Pages (from-to)1180-1185
Number of pages6
JournalBulletin of the Chemical Society of Japan
Issue number10
Publication statusPublished - 2020 Oct


  • C-F bond activation
  • Protodefluorination
  • Pt/Pd nanoalloy

ASJC Scopus subject areas

  • Chemistry(all)


Dive into the research topics of 'Pt-Pd nanoalloy for the unprecedented activation of carbon-fluorine bond at low temperature'. Together they form a unique fingerprint.

Cite this