Protein informatics towards function identification

Kengo Kinoshita, Haruki Nakamura

Research output: Contribution to journalReview articlepeer-review

59 Citations (Scopus)

Abstract

The study of structural genomics and structural proteomics has determined the tertiary structures of many hypothetical proteins, whose molecular functions could not be understood using conventional methods. In order to infer the geometrical location of the functional site, the biochemical function and the biological function of the hypothetical protein, much effort has been made in protein informatics. The importance of heterogeneous databases and various descriptors of amino acid sequences, tertiary structures and pathways on the proteome scale has been emphasised.

Original languageEnglish
Pages (from-to)396-400
Number of pages5
JournalCurrent Opinion in Structural Biology
Volume13
Issue number3
DOIs
Publication statusPublished - 2003 Jun 1
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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