Abstract
We examined the effect of Japanese green tea extract (JGTE) on enterohemorrhagic Escherichia coli (EHEC) O157:H7 infection in a gnotobiotic mouse model. Gnotobiotic mice inoculated with an EHEC strain developed neurologic and systemic symptoms, usually culminating in death. In contrast, none of mice receiving dietary JGTE showed clinical signs or death. This report describes the effect of JGTE, which includes the inhibition of bacterial growth in vivo. The Shiga-like toxin (SLT) level in the feces of the JGTE diet group was significantly lower than that of the control group.
| Original language | English |
|---|---|
| Pages (from-to) | 125-128 |
| Number of pages | 4 |
| Journal | MICROBIOLOGY and IMMUNOLOGY |
| Volume | 42 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1998 Jan 1 |
Keywords
- Escherichia coil O157
- Gnotobiotic mouse
- Japanese green tea
ASJC Scopus subject areas
- Microbiology
- Immunology
- Virology
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Cite this
Isogai, E., Isogai, H., Takeshi, K., & Nishikawa, T. (1998). Protective effect of Japanese green tea extract on gnotobiotic mice infected with an Escherichia coli O157:H7 strain. MICROBIOLOGY and IMMUNOLOGY, 42(2), 125-128. https://doi.org/10.1111/j.1348-0421.1998.tb02260.x