Protective effect of Japanese green tea extract on gnotobiotic mice infected with an Escherichia coli O157:H7 strain

Emiko Isogai; Hiroshi Isogai; Koichi Takeshi; Takeshi Nishikawa

doi:10.1111/j.1348-0421.1998.tb02260.x

Protective effect of Japanese green tea extract on gnotobiotic mice infected with an Escherichia coli O157:H7 strain

Emiko Isogai, Hiroshi Isogai, Koichi Takeshi, Takeshi Nishikawa

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33 Citations (Scopus)

Abstract

We examined the effect of Japanese green tea extract (JGTE) on enterohemorrhagic Escherichia coli (EHEC) O157:H7 infection in a gnotobiotic mouse model. Gnotobiotic mice inoculated with an EHEC strain developed neurologic and systemic symptoms, usually culminating in death. In contrast, none of mice receiving dietary JGTE showed clinical signs or death. This report describes the effect of JGTE, which includes the inhibition of bacterial growth in vivo. The Shiga-like toxin (SLT) level in the feces of the JGTE diet group was significantly lower than that of the control group.

Original language	English
Pages (from-to)	125-128
Number of pages	4
Journal	MICROBIOLOGY and IMMUNOLOGY
Volume	42
Issue number	2
DOIs	https://doi.org/10.1111/j.1348-0421.1998.tb02260.x
Publication status	Published - 1998 Jan 1

Keywords

Escherichia coil O157
Gnotobiotic mouse
Japanese green tea

ASJC Scopus subject areas

Microbiology
Immunology
Virology

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10.1111/j.1348-0421.1998.tb02260.x

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abstract = "We examined the effect of Japanese green tea extract (JGTE) on enterohemorrhagic Escherichia coli (EHEC) O157:H7 infection in a gnotobiotic mouse model. Gnotobiotic mice inoculated with an EHEC strain developed neurologic and systemic symptoms, usually culminating in death. In contrast, none of mice receiving dietary JGTE showed clinical signs or death. This report describes the effect of JGTE, which includes the inhibition of bacterial growth in vivo. The Shiga-like toxin (SLT) level in the feces of the JGTE diet group was significantly lower than that of the control group.",

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AU - Isogai, Emiko

AU - Isogai, Hiroshi

AU - Takeshi, Koichi

AU - Nishikawa, Takeshi

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Protective effect of Japanese green tea extract on gnotobiotic mice infected with an Escherichia coli O157:H7 strain

Abstract

Keywords

ASJC Scopus subject areas

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