Protective effect of Japanese green tea extract on gnotobiotic mice infected with an Escherichia coli O157:H7 strain

Emiko Isogai, Hiroshi Isogai, Koichi Takeshi, Takeshi Nishikawa

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

We examined the effect of Japanese green tea extract (JGTE) on enterohemorrhagic Escherichia coli (EHEC) O157:H7 infection in a gnotobiotic mouse model. Gnotobiotic mice inoculated with an EHEC strain developed neurologic and systemic symptoms, usually culminating in death. In contrast, none of mice receiving dietary JGTE showed clinical signs or death. This report describes the effect of JGTE, which includes the inhibition of bacterial growth in vivo. The Shiga-like toxin (SLT) level in the feces of the JGTE diet group was significantly lower than that of the control group.

Original languageEnglish
Pages (from-to)125-128
Number of pages4
JournalMICROBIOLOGY and IMMUNOLOGY
Volume42
Issue number2
DOIs
Publication statusPublished - 1998 Jan 1

Keywords

  • Escherichia coil O157
  • Gnotobiotic mouse
  • Japanese green tea

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Virology

Fingerprint Dive into the research topics of 'Protective effect of Japanese green tea extract on gnotobiotic mice infected with an Escherichia coli O157:H7 strain'. Together they form a unique fingerprint.

  • Cite this