Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells

Shota Yamazaki, Masahiko Harata, Yuya Ueno, Masaaki Tsubouchi, Keiji Konagaya, Yuichi Ogawa, Goro Isoyama, Chiko Otani, Hiromichi Hoshina

Research output: Contribution to journalArticle

Abstract

The effect of terahertz (THz) radiation on deep tissues of human body has been considered negligible due to strong absorption by water molecules. However, we observed that the energy of THz pulses transmits a millimeter thick in the aqueous solution, possibly as a shockwave, and demolishes actin filaments. Collapse of actin filament induced by THz irradiation was also observed in the living cells under an aqueous medium. We also confirmed that the viability of the cell was not affected under the exposure of THz pulses. The potential of THz waves as an invasive method to alter protein structure in the living cells is demonstrated.

Original languageEnglish
Article number9008
JournalScientific reports
Volume10
Issue number1
DOIs
Publication statusPublished - 2020 Dec 1

ASJC Scopus subject areas

  • General

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    Yamazaki, S., Harata, M., Ueno, Y., Tsubouchi, M., Konagaya, K., Ogawa, Y., Isoyama, G., Otani, C., & Hoshina, H. (2020). Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells. Scientific reports, 10(1), [9008]. https://doi.org/10.1038/s41598-020-65955-5