TY - JOUR
T1 - Prognostic Factors of Primary Lung Cancer. Assessment of Tumor Doubling Time in Survival
AU - Usuda, Katsuo
AU - Saito, Yasuki
AU - Aikawa, Hirokazu
AU - Chen, Yan
AU - Endo, Chiaki
AU - Takahashi, Satomi
AU - Kanma, Keiji
AU - Sato, Masami
AU - Sagawa, Motoyasu
AU - Fujimura, Shigefumi
PY - 1994/1/1
Y1 - 1994/1/1
N2 - A total of 174 cases with primary lung cancer was examined on survival. Survival rates were compared between some categories in each prognostic factor (univariate analyses), and significant factors affecting survival were obtained by multivariate analyses using Cox's proportional hazard model. Univariate analyses showed a significant difference in survival in relation to tumor doubling time (DT), age, sex, the way how a tumor was detected, smoking history, symptom, therapy, cell type, T factor, N factor, M factor and stage. Multivariate analyses using Cox's proportional hazard model in a stepwise fashion obtained a final set of four significant variables: N factor (p = 0.0001) therapy (p = 0.0016); DT (p = 0.0140) and M factor (p = 0.0421). DT was proved to be an independent and significant prognostic factor in lung cancer.
AB - A total of 174 cases with primary lung cancer was examined on survival. Survival rates were compared between some categories in each prognostic factor (univariate analyses), and significant factors affecting survival were obtained by multivariate analyses using Cox's proportional hazard model. Univariate analyses showed a significant difference in survival in relation to tumor doubling time (DT), age, sex, the way how a tumor was detected, smoking history, symptom, therapy, cell type, T factor, N factor, M factor and stage. Multivariate analyses using Cox's proportional hazard model in a stepwise fashion obtained a final set of four significant variables: N factor (p = 0.0001) therapy (p = 0.0016); DT (p = 0.0140) and M factor (p = 0.0421). DT was proved to be an independent and significant prognostic factor in lung cancer.
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U2 - 10.2482/haigan.34.1011
DO - 10.2482/haigan.34.1011
M3 - Article
AN - SCOPUS:0028555319
VL - 34
SP - 1011
EP - 1016
JO - Japanese Journal of Lung Cancer
JF - Japanese Journal of Lung Cancer
SN - 0386-9628
IS - 7
ER -