Production of salivary type α-amylase in human lung cancer

Nakamura Yusuke; Tomita Naohiro; Nishide Takahiro; Emi Mitsuru; Horii Akira; Ogawa Michio; Mori Takesada; Kosaki Goro; Okabe Tetsuro; Fujisawa Michio; Ohsawa Nakaaki; Kameya Toru; Matsubara Kenichi

doi:10.1016/0378-1119(89)90364-8

Production of salivary type α-amylase in human lung cancer

Nakamura Yusuke, Tomita Naohiro, Nishide Takahiro, Emi Mitsuru, Horii Akira, Ogawa Michio, Mori Takesada, Kosaki Goro, Okabe Tetsuro, Fujisawa Michio, Ohsawa Nakaaki, Kameya Toru, Matsubara Kenichi

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

α-Amylase, which is produced by lung cancer tissue, was studied by cloning cDNAs from a cell line originating from lung cancer that produces amylase. Sequencing studies with this cDNA showed that the expressing gene is of the salivary type. The specific location of the start point of transcription, as revealed by S1 mapping, supported this conclusion.

Original language	English
Pages (from-to)	107-112
Number of pages	6
Journal	Gene
Volume	77
Issue number	1
DOIs	https://doi.org/10.1016/0378-1119(89)90364-8
Publication status	Published - 1989 Apr 15

Keywords

Recombinant DNA
S1 mapping
amylase isozyme
cDNA
exons
nude mice
pseudogene
start point of transcription

ASJC Scopus subject areas

Genetics

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10.1016/0378-1119(89)90364-8

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Production of salivary type α-amylase in human lung cancer. / Yusuke, Nakamura; Naohiro, Tomita; Takahiro, Nishide; Mitsuru, Emi; Akira, Horii; Michio, Ogawa; Takesada, Mori; Goro, Kosaki; Tetsuro, Okabe; Michio, Fujisawa; Nakaaki, Ohsawa; Toru, Kameya; Kenichi, Matsubara.

In: Gene, Vol. 77, No. 1, 15.04.1989, p. 107-112.

Research output: Contribution to journal › Article › peer-review

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abstract = "α-Amylase, which is produced by lung cancer tissue, was studied by cloning cDNAs from a cell line originating from lung cancer that produces amylase. Sequencing studies with this cDNA showed that the expressing gene is of the salivary type. The specific location of the start point of transcription, as revealed by S1 mapping, supported this conclusion.",

keywords = "Recombinant DNA, S1 mapping, amylase isozyme, cDNA, exons, nude mice, pseudogene, start point of transcription",

author = "Nakamura Yusuke and Tomita Naohiro and Nishide Takahiro and Emi Mitsuru and Horii Akira and Ogawa Michio and Mori Takesada and Kosaki Goro and Okabe Tetsuro and Fujisawa Michio and Ohsawa Nakaaki and Kameya Toru and Matsubara Kenichi",

note = "Funding Information: We acknowledget he expert secretariala ssistance of Masami Inoue. This work was supported in part by a grant-in-aid to K.M. from the Ministry of Education, Science and Culture, Japan.",

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AU - Yusuke, Nakamura

AU - Naohiro, Tomita

AU - Takahiro, Nishide

AU - Mitsuru, Emi

AU - Akira, Horii

AU - Michio, Ogawa

AU - Takesada, Mori

AU - Goro, Kosaki

AU - Tetsuro, Okabe

AU - Michio, Fujisawa

AU - Nakaaki, Ohsawa

AU - Toru, Kameya

AU - Kenichi, Matsubara

N1 - Funding Information: We acknowledget he expert secretariala ssistance of Masami Inoue. This work was supported in part by a grant-in-aid to K.M. from the Ministry of Education, Science and Culture, Japan.

PY - 1989/4/15

Y1 - 1989/4/15

N2 - α-Amylase, which is produced by lung cancer tissue, was studied by cloning cDNAs from a cell line originating from lung cancer that produces amylase. Sequencing studies with this cDNA showed that the expressing gene is of the salivary type. The specific location of the start point of transcription, as revealed by S1 mapping, supported this conclusion.

AB - α-Amylase, which is produced by lung cancer tissue, was studied by cloning cDNAs from a cell line originating from lung cancer that produces amylase. Sequencing studies with this cDNA showed that the expressing gene is of the salivary type. The specific location of the start point of transcription, as revealed by S1 mapping, supported this conclusion.

KW - Recombinant DNA

KW - S1 mapping

KW - amylase isozyme

KW - cDNA

KW - exons

KW - nude mice

KW - pseudogene

KW - start point of transcription

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Production of salivary type α-amylase in human lung cancer

Abstract

Keywords

ASJC Scopus subject areas

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