Production of salivary type α-amylase in human lung cancer

Nakamura Yusuke, Tomita Naohiro, Nishide Takahiro, Emi Mitsuru, Horii Akira, Ogawa Michio, Mori Takesada, Kosaki Goro, Okabe Tetsuro, Fujisawa Michio, Ohsawa Nakaaki, Kameya Toru, Matsubara Kenichi

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

α-Amylase, which is produced by lung cancer tissue, was studied by cloning cDNAs from a cell line originating from lung cancer that produces amylase. Sequencing studies with this cDNA showed that the expressing gene is of the salivary type. The specific location of the start point of transcription, as revealed by S1 mapping, supported this conclusion.

Original languageEnglish
Pages (from-to)107-112
Number of pages6
JournalGene
Volume77
Issue number1
DOIs
Publication statusPublished - 1989 Apr 15

Keywords

  • Recombinant DNA
  • S1 mapping
  • amylase isozyme
  • cDNA
  • exons
  • nude mice
  • pseudogene
  • start point of transcription

ASJC Scopus subject areas

  • Genetics

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