Primary ependymoma in the posterior mediastinum

Sumiko Maeda, Satomi Takahashi, Kaoru Koike, And Masami Sato

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)


    A 46-year-old woman was referred to our hospital because of back pain and an abnormality on chest imaging. Chest computed tomography showed a well-delineated tumor in the left paravertebral space. Histological analysis of the resected tumor revealed perivascular pseudorosettes, and immunoreactivity for glial fibrillary acidic protein established the diagnosis of ependymoma. A few cases have been reported in the ovary, broad ligament, sacrococcygeal region, lungs, and mediastinum, but the pathogenesis has not yet been clarified. Female predominance in these tumors and organogenesis of the sites may suggest a key to the pathogenesis.

    Original languageEnglish
    Pages (from-to)494-497
    Number of pages4
    JournalAnnals of Thoracic and Cardiovascular Surgery
    Issue number5
    Publication statusPublished - 2011 Oct 25


    • Embryology
    • Ependymoma
    • Female
    • Mediastinal tumor

    ASJC Scopus subject areas

    • Surgery
    • Pulmonary and Respiratory Medicine
    • Cardiology and Cardiovascular Medicine
    • Gastroenterology


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