Primary aldosteronism due to unilateral adrenal microadenoma in an elderly patient: Efficacy of selective adrenal venous sampling

Yoshiaki Tamura, Jun Ichiro Adachi, Yuko Chiba, Seijiro Mori, Kazuhiro Takeda, Yutaka Kasuya, Takeo Murayama, Motoji Sawabe, Hironobu Sasano, Atsushi Araki, Hideki Ito, Toshiyuki Horiuchi

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

We encountered a case of drug-resistant hypertension and hypokalemia. Laboratory data suggested primary aldosteronism (PA). Computed tomography imaging appeared normal for a long duration with a left-sided nodule appearing far later; adrenal scintigraphy was first normal, and the second test showed right-sided uptake. However, a repeat selective adrenal venous sampling (SAVS) indicated a left-sided lateralization of the hypersecretion of aldosterone. Left adrenectomy was performed, and his clinical symptoms improved. The histopathological findings demonstrated the aldosterone-producing microadenoma with secondary micronodules. In conclusion, SAVS should be performed to determine the laterality of PA with obscure CT imaging.

Original languageEnglish
Pages (from-to)37-42
Number of pages6
JournalInternal Medicine
Volume47
Issue number1
DOIs
Publication statusPublished - 2008 Jan 1

Keywords

  • Adrenal microadenoma
  • Primary aldosteronism
  • Selective adrenal venous sampling (SAVS)

ASJC Scopus subject areas

  • Internal Medicine

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