Abstract
Leukemic cells from nine patients with adult T-cell leukemia were examined for Fcγ and Fcμ receptors, human B-lymphocyte antigens (HBLA), and effect on PWM-induced B-cell differentiation. Fcγ receptors were detected in one and Fcμ receptors in another. Leukemic cells in both cases bore HBLA and expressed a suppressive effect on PWM-induced B-cell differentiation. However, leukemic cells from the remaining seven cases did not bear Fc receptors. In four, leukemic cells possessed HBLA and all expressed a suppressive effect on the PWM system. Some leukemic cells which did not express HBLA had the same effect on the PWM system. The origin of adult T-cell leukemia was discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 287-295 |
| Number of pages | 9 |
| Journal | Clinical Immunology and Immunopathology |
| Volume | 17 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1980 Jan 1 |
| Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Pathology and Forensic Medicine
- Immunology
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Hattori, T., Uchiyama, T., Takatsuki, K., & Uchino, H. (1980). Presence of human B-lymphocyte antigens on adult T-cell leukemia cells. Clinical Immunology and Immunopathology, 17(2), 287-295. https://doi.org/10.1016/0090-1229(80)90098-7