Preparation of trans-2-allyl-6-alkyl(aryl)-1,2,3,6-tetrahydropyridines by reductive trans-2,6-dialkylation of pyridine. Synthesis of (±)-epidihydropinidine

Yuri N. Bubnov, Elena V. Klimkina, Anatoly V. Ignatenko, Ilya D. Gridnev

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

A convenient method for the preparation of the title compounds involving the sequential treatment of pyridine with RLi (R = Alk, Ar), triallylborane and methanol is developed.

Original languageEnglish
Pages (from-to)1317-1320
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number8
DOIs
Publication statusPublished - 1996 Feb 19
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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